1295 FETAL PRIMIDONE EFFECTS
نویسندگان
چکیده
منابع مشابه
Dmm020594 1295..1309
Medulloblastoma (MB) is the most common malignant primary pediatric brain tumor and is currently divided into four subtypes based on different genomic alterations, gene expression profiles and response to treatment: WNT, Sonic Hedgehog (SHH), Group 3 and Group 4. This extensive heterogeneity has made it difficult to assess the functional relevance of genes to malignant progression. For example,...
متن کاملThe effects of phenytoin on phenobarbitone and primidone metabolism.
Serum concentrations of primidone and its metabolites-phenobarbitone and phenylethylmalonamide-were measured in 40 epileptic patients receiving treatment with primidone alone or primidone plus phenytoin. Serum phenobarbitone concentrations were also measured in 100 patients receiving phenobarbitone, alone or with phenytoin showed raised serum phenobarbitone concentrations. Phenytoin also caused...
متن کاملNpgRJ_Nn_1535 1295..1297
It is unclear how knowledge of one’s actions and one’s body contribute to the understanding of others’ actions. Here we show that two subjects lacking cutaneous touch and sense of movement and position show a selective deficit in interpreting another person’s anticipation of weight when seeing him lifting boxes. We suggest that this ability occurs through mental simulation of action dependent o...
متن کاملPrimidone intoxication in a child.
Primidone has been a valuable drug in the treatment of epilepsy since the early 1950's. It is akin to phenobarbitone (see Fig.) in which the carbon atom at the 'two' position in the pyrimidine ring has two hydrogens instead of a carbonyl oxygen. Bogue and Carrington developed the drug in 1949, and reported on its effectiveness in experimental animals (Bogue and Carrington, 1953). Clinical trial...
متن کاملMegaloblastic anemia following the use of primidone.
HILE the umsderhyimmg causes of the nsajority of misegaloblast-ic amsemssias are usow knsown, the list is usotyet exhaustive amid it has recemstly been suggested that amsticomsvulsammt drutgs nsay commstitute a mies ’ etiohogic fact-or its sonic cases. The postulated effectof these drutgs is particutlarly strikimsg ins that megaloblastic ausemia is msot seems wit-h the niomispecific toxic agcmm...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1985
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198504000-01319